Projects / Programmes source: ARIS

Prognostic value of uPA, PAI 1 and PAI 2 in solid tumors

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Research activity

Code Science Field Subfield
3.04.00  Medical sciences  Oncology   

Code Science Field
B007  Biomedical sciences  Medicine (human and vertebrates) 
B200  Biomedical sciences  Cytology, oncology, cancerology 
Keywords
plasminogen activator, plasminogen activator inhibitors, prognosis, breast cancer, bladder cancer
Evaluation (metodology)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Organisations (3) , Researchers (17)
0302  Institute of Oncology Ljubljana
no. Code Name and surname Research area Role Period No. of publications
1.  08616  PhD Matej Bračko  Oncology  Researcher  1997 - 1999  197 
2.  15832  Olga Cerar  Oncology  Researcher  1997 - 1999  100 
3.  03289  Jožica Červek  Oncology  Researcher  1997 - 1999  205 
4.  12179  PhD Tanja Čufer  Oncology  Head  1997 - 1999  782 
5.  15834  PhD Tanja Južnič Šetina  Oncology  Researcher  1997 - 1999  60 
6.  12224  PhD Borut Kragelj  Oncology  Researcher  1997 - 1999  82 
7.  05278  PhD Jurij Lindtner  Oncology  Researcher  1997 - 1999  163 
8.  15835  MSc Bojana Pajk  Oncology  Researcher  1997 - 1999  86 
9.  08754  Gabrijela Petrič-Grabnar  Oncology  Researcher  1997 - 1999  66 
10.  08750  PhD Zvonimir Rudolf  Oncology  Researcher  1997 - 1999  258 
11.  08800  PhD Gregor Serša  Oncology  Researcher  1997 - 1999  1,598 
12.  00712  PhD Janez Škrk  Oncology  Researcher  1998 - 1999  178 
13.  07195  PhD Ivan Vrhovec  Oncology  Researcher  1997 - 1999  120 
14.  11747  PhD Branko Zakotnik  Oncology  Researcher  1997 - 1999  435 
0381  University of Ljubljana, Faculty of Medicine
no. Code Name and surname Research area Role Period No. of publications
1.  07187  PhD Andrej Mašera  Oncology  Researcher  1998 - 1999  134 
2.  07228  PhD Zdenka Ovčak  Oncology  Researcher  1998 - 1999  78 
1538  University of Ljubljana, Faculty of Electrical Engineering
no. Code Name and surname Research area Role Period No. of publications
1.  05071  PhD Ankica Babič  Computer science and informatics  Researcher  1998 - 1999  104 
Abstract
The prognosis of cancer patients depends largely on the ability of cancer cells to invade the surrounding tissue and to metastasize. These processes are influenced by tumor-associated proteases among which serine proteases and their inhibitors may play a central role. The aim of our study is to determine the content of serine protease uPA and its inhibitors PAI 1 and PAI 2, in primary tumors of the breast and urinary bladder, and to establish their prognostic value. It is hoped that the results of our study could be used for a more rational treatment planning in patients with primary cancers of the breast and urinary bladder, thus improving their survival.
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