The study concerned changes in vascular and autonomic cardiac function in adults following the tetralogy Fallot (ToF) operation. It was found that the heart rate variability (time domain) and heart rate recovery were truncated by ToF compared to healthy peers. The latter was also significantly associated with the pulse wave velocity.
COBISS.SI-ID: 7992339
A study on the correlation of inflammatory parameters in peripheral blood with the degree of inflammation in atherosclerotic plaques. It turned out that the degree of inflammation of the atherosclerotic plaque, as demonstrated by the rate of injection of the labelled glucose, correlates with the level of inflammatory markers in the peripheral blood.
COBISS.SI-ID: 3546796
In the research unit on peripheral arterial disease, a PID-PAB study was completed and published. It monitored overall survival and survival without vascular complications in patients with peripheral arterial disease who received optimal preventive measures for cardiovascular disease prevention. Conclusions show that patients with peripheral arterial disease had a higher risk of death and cardiovascular complications than control subjects despite preventive cardiovascular action, but that cardiovascular complications were no longer the leading cause of death in that population.
COBISS.SI-ID: 33205209
In rats, preventive action of low-dose fluvastatin, valsartan, and particularly their combination on the arterial wall has been shown to be more effective than the action of high, therapeutic doses. It turned out that all functional parameters (endothelium depend relaxation of the thoracic aorta, ischemic reperfusion injury of the myocardium), as well as the biochemical paramteres (increase in nitric oxide, reduction of asymmetric dimethylarginine), as well as the favorable expression of genes (for nitric oxide synthase) were mostly improved by use of a low dose combination of fluvastatin and valsartan.
COBISS.SI-ID: 4146604
A study was completed and published in which arterial stiffness, endothelial function of digital arteries and coronary calcium burden were monitored in patients with essential thrombocythemia without developed atherosclerotic disease. Patients with essential thrombocythemia have been shown to have an increased calcium burden, indicating high coronary risk, which was not detected by the Framingham equation. Otherwise, this population did not differ from healthy subjects in other measured parameters of the arterial function.
COBISS.SI-ID: 4162476