This invited advanced review describes the role of microRNAs in skeletal muscle development, growth, atrophy and disease. As global yet specific muscle regulators, myomirs are also good candidates for therapeutic use. We summarize the various approaches based on miRNA that have so far been attempted in treatment of atrophy. The review offers a perspective on the current state-of-the-art regarding normal myomir expression dynamics and their role in development of various diseases. Both are necessary to determine their potential for muscle atrophy prevention.
B.06 Other
COBISS.SI-ID: 27698983