1.

Toward a true bacteriotherapy for Clostridium difficile infection

This paper describes current research and future perspectives of treatment of C. difficile infections that is based on gut microbiome restoration.

COBISS.SI-ID: 512496184

2.

Pan-European longitudinal surveillance of antibiotic resistance among prevalent Clostridium difficile ribotypes

Clostridium difficile infection remains a major healthcare burden. We report results of epidemiological and antimicrobial susceptibility investigations of C. difficile isolates collected prior to fidaxomicin introduction, establishing important baseline data. Thirty-nine sites in 22 countries submitted a total of 953 C. difficile isolates for PCR ribotyping, toxin testing, and susceptibility testing. There was a significant correlation between lack of ribotype diversity and greater antimicrobial resistance (measured by cumulative resistance score). This raises the possibility of antimicrobial exposure as the underlying reason for their appearance, and highlights the need for ongoing epidemiological and antimicrobial resistance surveillance.

COBISS.SI-ID: 512579640

3.

Continuous production of bacteriophages

The chapter describes continuous production of bacteria and bacteriophages. The methodology could be used for cultivation of bacterial cultures, microbial communities, and propagation of bacteriophages.

COBISS.SI-ID: 4505720