Thirty-two dogs treated for preiodontal disease were divided in two groups according to the level of periodontal disese and compared to dogs with no periodontitis. Blood was tested before and 2 weeks after treatment for nitrosyl hemoglobin (HbNO), nitrate/nitrite (NOx), and 3-nitrotyrosine (NT) levels. After treatment a noticeable increase in NOx plasma level was observed in group with generalised form of periodontal disese. The results suggest that after periodontal treatment the blood level of NO increased as a systemic response to treatment.
COBISS.SI-ID: 3600506
Aim:To assess the prevalence of molar incisor hypomineralisation (MIH) in children in Slovenia and explore the relationship between MIH defects and caries in the primary and permanent dentition, and tooth- and surface-specific associations between MIH defects and caries on first permanent molars (FPM).Materials and methods:The study population was comprised of 558 children aged 6.011.5 years. The prevalence of developmental defects of enamel (DDE) on FPM and permanent incisors was assessed through clinical examination by a calibrated examiner using the modified DDE Index of the FDI. Also recorded were atypical fillings, post-eruptive enamel breakdowns, and extractions because of MIH. Dental caries was assessed using the WHO criteria.Results: At least one FPM with MIH defects was found in 21.4% of children. Children with MIH had significantly higher (p(0.05) caries experience in their permanent teeth. In primary teeth, higher caries experience was not statistically significant. MIH defects in FPM were associated with higher caries scores at the tooth (p(0.01), and at the surface (p(0.05) level. Conclusion: MIH is common in Slovenia. Children with MIH are more prone to dental caries development on their permanent teeth. On FPM teeth and surfaces affected with MIH defects, even with only mild demarcated opacities with apparently intact enamel, an increased caries experience is present.
COBISS.SI-ID: 31033817
Objective: Excess fluoride intake during tooth development is known to cause dental fluorosis. It has also been suggested that amoxicillin use in early childhood is associated with enamel hypomineralization. The aim was to investigate separate and combined effects of sodium fluoride (NaF) and amoxicillin on enamel formation in vitro. Design: Mandibular molar tooth germs of E18 mouse embryos were cultured for 10 days in a medium containing NaF (10, 12 or 15 microM) and/or amoxicillin (0.5, 1, 2 or 3.6 mg/mL) or sodium clavulanate (0.07 mg/mL) alone or in combination with 0.5 mg/mL of amoxicillin. Morphological changes were studied from the whole tooth photographs and histological tissue sections with light microscope. Results: Only with the highest concentrations of NaF or amoxicillin alone the extent of enamel in the first molars measured as the vertical enamel height/crown height ratio was reduced ( p ( 0.01, p ( 0.001, respectively). At lower concentrations, combination of NaF (12 microM) and amoxicillin (2 mg/mL) significantly reduced enamel extent compared with the controls ( p ( 0.001). Histologically, the ameloblasts were still columnar but poorly organized and the nascent enamel was often non-homogeneous. Enamel formation was not seen in any second molars exposed to 12 microM NaF and 2 mg/mL of amoxicillin (or higher concentrations) compared with the presence of enamel in half of the controls ( p ( 0.001). Conclusions: Amoxicillin and NaF dose dependently affect developing enamel of mouse molars in vitro and the effects are potentiative. The clinical significance of the results remains to be studied.
COBISS.SI-ID: 31221977
The aim of the present study was to evaluate the association of tongue posturewith the dentoalveolar maxillary and mandibular morphology in a group of Class III subjects in comparison to a group of Class I subjects. Twenty Class III subjects (9 males, 11 females, 19.2 +/- 4.6 years) and 20 Class I subjects (6 males, 14 females, 17.4 +/- 1.7 years) were included in the present study. Maxillary and mandibular morphology was defined by the intermolar and intercanine distances, at both the cusps and gingival levels, and by measuring surface area and volume of the palatal vault and mouth floor assessed on three-dimensional digital models. Tongue-to-palate distances were measured on lateral cephalograms. The groups were compared using the Mann-Whitney U-test and correlations between each morphological parameter and the tongue-to-palate distances were calculated using the Spearman correlation coefficient. The mandibular intermolar width at the gingival level was significantly greater in the Class III group (P ( 0.01), while the maxillary intercanine widths were significantly smaller in the Class III group (P ( 0.05). The mouth floor area and volume and the respective ratios between the mouth floor and palate were significantly greater in the Class III group (P = 0.01). The tongue-to-palate distances were generally greater, i.e. lower tongue posture, for the Class III subjects. Significant correlations were seenbetween tongue-to-palate distances in the posterior region with the area ratio (rho = 0.44, P ( 0.05). Tongue posture is significantly lower in Class III subjects and is associated with the dentoalveolar characteristics of the maxilla and mandible.
COBISS.SI-ID: 29691609
The aim of this study was to evaluate the influence of prolonged sucking habits and mouth breathing on palatal vault morphology in a group of subjects with unilateral functional crossbite šcrossbite (CB) groupđ compared with a group of subjects with normal occlusion šnon-crossbite (NCB) groupđ. A sample of 80 Caucasian subjects (51 CB and 29 NCB; aged 5.3 0.8 years) in the deciduous dentition was selected. A questionnaire regarding the subjectćs sucking habits was answered by the parents. Any sucking habit that lasted morethan 24 months was considered as a prolonged sucking habit. The breathing pattern was assessed by an experienced otorinolarygologist and was classified either mainly nose or mouth breathing. Intercanine and intermolar distances and palatal surface area and volume were recorded three dimensionally on studycasts. Univariate and multivariate analyses were employed. Posterior CB was negatively correlated with all the dental and palatal parameters (P ( 0.01) with the exception of the palatal surface area that did not reach the statistical significance. Only prolonged sucking habits (but not mouth breathing) was a significant risk indicator for unilateral functional CB (P ( 0.001). However, the prolonged sucking habits were not significantly correlated with any of the investigated parameter, and mouth breathing was negatively correlated with the intermolar distance only. Therefore, maxillary constriction in unilateral functional CB might not be influenced by the presence or absence of prolonged sucking habits or mouth breathing.
COBISS.SI-ID: 30180057