L3-4171 — Final report
1.
Modified bone density-dependent orthotropic material model of human mandibular bone

The prediction accuracies of computationally simulating various biomechanical complex problems of human bones depends on proper modelling of the problem’s geometries and boundary conditions but it are also essentially dependent on proper descriptions of the mechanical properties of all the constitutive elements. As the human mandibular bone is a very important load-carrying element in biomechanics, the main aim of this research was to develop an innovative, not yet described in literature, spatial and bone density-dependent orthotropic material model of the human mandibular bone for use during computational simulations. We compared it with the more commonly used constitutive material models for computational simulations of the human mandibular bone behaviour with inserted dental implant. The results show that the von Mises equivalent (EQV) stress distribution values in the bone density-dependent orthotropic model are higher in comparison with other models but the highest are on the top of the alveolar ridge and higher in the lingual than in the buccal part of the lower jaw.

COBISS.SI-ID: 1764524
2.
A novel method of dental panoramic tomogram analysis

Objective: The purpose of this study was to test a new method of dental panoramic tomogram (DPT) analysis to show the differences of mandibular bone volume and relative bone density (RBD) in order to detect osteoporosis. Materials and methods: A case-control study compared 62 women with osteoporosis (O) and 24 women with osteopenia (o) to a control group of 33 women with normal bone mineral density (N). DPTs were analyzed using an original method resulting in anatomic and RBD indexes as well as using previously described methods: panoramic mandibular index (PMI) and mandibular cortical width (MCW). Results: One anatomic and four RBD indexes differed statistically significantly between the group O and N and three RBD indexes differed statistically significantly between o and N. PMI did not show statistically significant differences between the groups. The MCW differed significantly at two measured sites between O and N. Conclusions: Average values of RBD indexes were statistically significantly different between O and N and also between o and N. Important differences regarding RBD were confirmed using a new and original method of common DPT analysis. This method could serve as a screening tool for osteoporosis.

COBISS.SI-ID: 30636249
3.
Satisfaction of Patients Treated with Implant-Supported Mandibular Overdenture Compared to Patients Treated with Conventional Denture

Backgrounds. Treatment of total edentulism with implant-supported overdenture is an established alternative to the conventional removable denture, especially in the case of poor anatomical conditions in the mandible. The aim of our study was to estimate the difference in satisfaction based on the quality oflife aspect in totally edentulous Slovenian patients treated with mandibular implant-supported overdentures or conventional removable dentures by using a standardized questionnaire. Methods. The study enrolled 50 patientstreated with mandibular implant-supported overdentures and 63 patientstreated with conventional removable dentures. This number also includes 8 patients with very po or anatomical conditions who were followed-upprospectively and asked to rate their satisfaction with the prostheses prior to and after treatment with implant-supported overdentures. The patients were asked to complete a custom questionnaire about their generalhealth and prosthetic treatment and the standardized Oral Health Impact Profile questionnaire, which assesses physical dysfunction as well as the social and psychological influence ofvarious dysfunctions and diseases of the stomatognathic system and their influence on general health. Results. Patients treated with implant-supported overdenture are generally more satisfied than those treated with conventional removable dentures (p ( 0.01), which is even more obvious in the prospectively assessed group of patients. Questions for assessing functionallimitations of the stomatognathic system andprosthetic appliances and physical pain in the stomatognathic system yielded statistically significant differences (p::; 0.05) between the two group s in ~ 50% of answers. In other group s of questions assessing psychosocial and general handicap, a statistically significant difference (p::; 0.05) was found in less than 50% of answers in a particular group of questions. (Abstract truncated at 2000 characters)

COBISS.SI-ID: 29424857
4.
Bacterial causes of odontogenic abscess and phlegmon and their in vitro susceptibility to antibiotics

Introduction: Odontogenic abscess and phlegmon are acute suppurative infections caused mainly by mixed aerobic and anaerobic bacteria which are part of the normal oral microflora. The treatment is based on wide incision and drainage, removal of the cause of infection, and supportive antibiotic therapy according to strict indications. The aim of this study was to isolate the causative agents of odontogenic abscesses and phlegmons, standardize the method of specimen collection for microbiological investigation, and estimate the in vitro susceptibility of the causative bacteria to the most frequently used antibiotics and moxifloxacin. Patients and methods: Fifty patients with odontogenic abscesses and phlegmons were included in this prospective study. Results: Aerobic bacteria were isolated as the predominant causative agents in 39% of specimens, anaerobic bacteria were predominant in 60% of specimens, and yeasts in 1% of specimens. Among the aerobic isolates, 96% were susceptible to penicillin and 93% to clindamycin. Among the anaerobes, 84% were susceptible to penicillin, 100% to amoxicillin with clavulanic acid, 94% to clindamycin, and 82% to metronidazole. All aerobic and anaerobic isolates (100%) were susceptible to moxifloxacin. Conclusion: In our study, the causative agents of odontogenic abscesses and phlegmons were mixed aerobic and anaerobic bacteria. Penicillin remains the antibiotic of first choice in empirical treatment of odontogenic infection. Clindamycin is usedin patients allergic to penicillin.

COBISS.SI-ID: 30354905
5.
Prelaminated temporal fascia free flap for reconstruction of the floor of the mouth

Background: Mucosal defects after resection of the malignant disease in oral cavity can be left to heal by secondary intention, covered with free skin grafts or covered with local, regional or microvascular flaps. Decision about reconstruction depends on the defect size, quality of surrounding tissues and the patient's general health condition. The goal of reconstruction is to achieve elastic, soft and moist surrounding, which enables the functioning of the remaining structures in the oral cavity as well as arapid functional and social rehabilitation. Methods: At the beginning of patient's diagnostic workup, two pieces of clinically healthy buccal mucosa were harvested and transferred as free mucosal grafts under superficial temporal fascia. After three weeks, squamous carcinoma of the floor of the mouth was resected and mucosai defect was reconstructed with a prelaminated temporalis fascia microvascular flap. Results: Presented and discussed is a reconstruction of the oral mucosa defect rarely described in the literature. Conclusion: There is no ideal replacement for the oral mucosa. Scar as a result of healing by secondary intention prevents tongue mobility. The quantity of mucosa availablefor local flaps is limited. Oral cavity environment is not ideal for healing of split-thickness skin grafts and skin transferred into oral cavity is never accustomed to the local conditions. With buccal mucosa prelaminated temporal fascia, microvasculary transferred into the oral cavity, offers a valuable method of reconstruction of medium-size mucosal defects of the oral cavity in selected, motivated patients.

COBISS.SI-ID: 28187609