1.

Ferri-liposomes, a novel MRI-visible drug-delivery system, enabled successful tumor treatment by efficient cysteine cathepsins inhibition

An overview of protease inhibition in cancer treatment was given with the emphasis on cysteine proteases. The results demonstrating that cysteine cathepsins could be target for tumor treatment; however, the use of efficient drug delivery systems could be beneficial for improving the therapeutic index. Thus, the notion that regulation of proteases activity in pathological conditions is critical in many pathological conditions including tumor progression was also presented.

B.04 Guest lecture

COBISS.SI-ID: 25513255

2.

The role of stefin B depletion in mammary tumor progression and metastatis.

A discussion on the role of endogenous cysteine cathepsins inhibitors, as stefin B and cystatin C, have been presented. Moreover, the possible impacts of both inhibitors at different stages of cancer progression and metastasis has been proposed. The results of inhibition of tumor growth upon depletion of stefin B in transgenic mouse mammary cancer model have been also presented.

B.03 Paper at an international scientific conference

COBISS.SI-ID: 25636647