J3-4108 — Annual report 2013
1.
A 32-month follow-up study of nanovesicle concentrations in blood from 12 patients with gastrointestinal stromal tumour treated with imatinib

Concentration of nanovesicles in isolates from peripheral blood of 6 patients treated due to gastrointestinal stromal tumor was followed for 32 months. We found that the concentration increased in the beginning of the treatment, but decreased to normal values in about 1 month.

COBISS.SI-ID: 9629012
2.
Extracellular vesicle-mediated transfer of membranous components from the highly malignant T24 urinary carcinoma cell line to the non-malignant RT4 urinary papilloma cell line

We reported the first experimental evidence that in bladder cancer model membranous components, labelled with DiO and Cholera toxin subunit B (CtB), can be transported from highly malignant (T24) to non-malignant (RT4) cells by extracellular vesicles (EVs). Taking into account the presence of stable membranous nanostructures, found by scanning electron microscopy, we suggested a possible uptake mechanism in recipient cells, namely through fusion with highly curved membranous regions.

COBISS.SI-ID: 10148948
3.
Effect of engineered TiO2 and ZnO nanoparticles on erythrocytes, platelet-rich plasma and giant unilamelar phospholipid vesicles

TiO2 and ZnO EPs caused erythrocyte aggregation and pletelet activation and could be potentially prothrombogenic, while ZnO could also cause membrane rupture.

COBISS.SI-ID: 7420281