1.

Membrane vesicles as biomarkers of homeostasis

The work was awarded with the UNESCO l'Oreal prize form women in science. We considered mechanisms of microvesiculation, elaborated clinical studies of concentration of microvesicles from blood in patients with gastrointestinal diseases and proved microvesicle-mediated transfer of matter between cell lines of diferent types.

D.09 Tutoring for postgraduate students

COBISS.SI-ID: 10378580

2.

Mechanisms of vesiculation of biological membranes

We considered stability of membranos nanostructures theoretically and experimentally. We have shown that narow necks are stable structures in models of artificial membranes and that self-adhesion of buds takes place also in cells.

D.09 Tutoring for postgraduate students

COBISS.SI-ID: 10643540

3.

Importance of cell membrane microvesiculation in gastrointestinal carcinoma

We found that in patients with gastrointestinal carcinoma the concentration of microvesicles in isolates from blood is increased while the ability of plasma to mediate attractive interaction between membranes is decreased.

D.09 Tutoring for postgraduate students

COBISS.SI-ID: 1688492

4.

Method for treatment of tools and tools used for isolation of microvesicles, nanovescicles or exsomes

We developed a method for elaboration of material with ionic plasma. Due to this elaboration the surface becomes structures and microvesicles in the process of isolation exhibit less adhesion.

F.32 International patent

COBISS.SI-ID: 28412967

5.

Role of blood sampling in assessment of concentration of extracellular nanovesicles in isolates from peripheral blood

We found that shear forces during blood flow through the needle increases concentration of EVs in isolates. We suggest the optimal dimensions of needle to minimize artefact.

F.22 Improvement to existing health/diagnostic methods/procedures

COBISS.SI-ID: 5476378