A web server ProBiS, freely available at http://probis.cmm.ki.si, is presented in this article. This provides access to the program ProBiS (Protein Binding Sites), which detect protein binding sites based on local structural alignments.
COBISS.SI-ID: 4404506
An algorithm, ProBiS is developed that detects structurally similar sites on protein surfaces by local surface structure alignment. It compares the query protein to members of a database of protein 3D structures and detects with sub-residue precision, structurally similar sites as patterns of physicochemical properties on the protein surface using an efficient maximum clique algorithm. The algorithm has been used successfully for the detection of protein-protein,protein-small ligand and protein-DNA binding sites.
COBISS.SI-ID: 4395802