J3-3624 — Annual report 2012
1.
Regulating colicin synthesis to cope with stress and lethality of colicin production

Numerous mechanisms at the level of transcription and posttranscriptionally ensure that colicins are produced only in cells exposed to extreme stress such as DNA damage and starvation.

COBISS.SI-ID: 2687055
2.
Colicin insensitivity correlates with a higher prevalence of extraintestinal virulence factors among Escherichia coli isolates from skin and soft-tissue infections

Analysis of resistence agaisnt colicins and virulence factors of pathogenic as well as commensal Escherichia coli strains revealed their correlation.

COBISS.SI-ID: 2552399
3.
Double locking of an Escherichia coli promoter by two repressors prevents premature colicin expression and cell lysis

Repressors LexA and IscR inhibit expression of the colicin K gene, cka. iscR stabilizes lexA binding to operator sequences and provokes a delay in cka exčpression following DNA damage providing bacterial cells time to repair DNA damage.

COBISS.SI-ID: 2608719