In the study of absorption and metabolismof phenolics an intravenous dose of fruit pigment cyanidin 3-glucoside was administered to rats and tissues were analyzed using last-generation mass spectrometry. As soon as 15 s after its administration, both cyanidin 3-glucoside and its methylation product, peonidin 3-glucoside, were detected in the plasma, kidneys, and liver. These data about fast kinetics contribute to solving the paradox of the high bioactivity of anthocyanins in spite of their apparent low bioavailability. Data were also published as key scientific article in Global Medical Discovery: http://globalmedicaldiscovery. com/key-scientific-articles/exceptionally-fast-uptake-and-metabolism-of-cyanidin-3-glucoside-by-rat-kidneys-and-liver/.
COBISS.SI-ID: 3608168
Epidemiological studies suggest that diets rich in fruits and vegetables decrease the risk of cardiovascular diseases. This seems to be related to the intake of polyphenols. This study was aimed, at confirming the expression of bilitranslocase in the rat aorta and in isolated endothelial cells and verifying the hypothesis that bilitranslocase may mediate the specific uptake of flavonoids therein. The data obtained suggest that flavonoids are rapidly taken up into the endothelium via bilitranslocase.
COBISS.SI-ID: 3036776
For the determination of glutathione content a modified preparation of sample with high performance liquid chromatography (HPLC) with fluorescence detection (FLD) and on-line pre-column derivatization in grape juice and wine was developed. The average glutathione content in 28 young Sauvignon Blanc wines was 12.5 mg/L.
COBISS.SI-ID: 3347048
For the first time phenolics from bilberries (Vaccinium myrtillus L.) sampled from seven different locations and highbush blueberries (Vaccinium corymbosum L.) from one location in Slovenia were analyzed. In samples of both species 15 anthocyanins were identified and quantified. As well the contents of flavanols, flavonols, phenolic acids, and stilbenes were determined.
COBISS.SI-ID: 3921528