In the study we have compare two distinct method for determination of intrathecal synthesis of borrelial antibodies, IDEA Lyme Neuroborreliosis and calculation of the LIAISON results according to Reiber. The comparison did not reveal substantial differences. Intrathecal synthesis was once again found to be useful diagnostic marker, most frequently determined in the group of patients with clinically confirmed Lyme neuroborreliosis. The relatively low sensitivity can be explained with the short duration of clinical symptoms and the consequent absence of synthesis of specific antibodies.
B.06 Other
COBISS.SI-ID: 26602713The aim of the present study was to demonstrate the immune response in serum and cerebrospinal fluid of patients with (suspected) Lyme neuroborreliosis with two distinct serological assays. Using LIAISON specific CSF antibodies were detected in 62 % patients with LNB, 0 % patients with sLNB and in 13 % patients with TBE. Corresponding values for IgG antibodies are 59 %, 15 % and 25 %. With ELISA we were able to demonstrate specific IgM antibodiesin 21% patients with LNB, 0 % patients with sLNB and in 0 % patients with TBE. Corresponding values for IgG antibodies were 41 %, 0 in 3 %.
B.03 Paper at an international scientific conference
COBISS.SI-ID: 25668057