We evaluated the clinical importance of small and larger uterine septum in a retrospective matched control study of 2481 embryo transfers. Pregnancy rates after embryo transfer before hysteroscopic metroplasty were significantly lower, both in women with subseptate and septate uterus and in women with arcuate uterus compared with controls. If two or three embryos with at least one best-quality embryo were transferred, the differences were 9.6% versus 43.6%, OR 7.3 (P ( 0.001) and 20.9% versus 35.5%, OR 2.1 (P ( 0.03), respectively. Differences in terms of live birth rates were even more evident: 1.9% versus 38.6%, OR 32 (P ( 0.001) and 3.0% versus 30.4%, OR 14 (P ( 0.001). After surgery, the differences disappeared.
COBISS.SI-ID: 27355609
The HyCoSy procedure is well tolerated and can be used as a primary tool in investigation of infertile women . Its sensitivity is comparable to the sensitivity of hysterosalpingography.
COBISS.SI-ID: 512102713
Modified method for blastocyst freeze-thawing provides good clinical results. It offers the possibility for a single-thawed blastocyst transfer and represents a good alternative for older women because of its lower of spontaneous abortion.
IVF in the modified natural IVF cycle can be successful used in women younger than 40 years of age having a normal ovarian reserve. The prognosis of IVF older than 39 years of age, with reduced ovarian reservee has been reduced.