1.

Double locking of an Escherichia coli promoter by two repressors prevents premature colicin expression and cell lysis

Repressors LexA and IscR inhibit expression of the colicin K gene, cka. iscR stabilizes lexA binding to operator sequences and provokes a delay in cka exčpression following DNA damage providing bacterial cells time to repair DNA damage.

COBISS.SI-ID: 2608719

2.

Regulating colicin synthesis to cope with stress and lethality of colicin production

Numerous mechanisms at the level of transcription and posttranscriptionally ensure that colicins are produced only in cells exposed to extreme stress such as DNA damage and starvation.

COBISS.SI-ID: 2687055

3.

Interconversion between bound and free conformations of LexA orchestrates the bacterial SOS response

A conformational change in the LexA protein occurs upon DNA binding.

COBISS.SI-ID: 2368847

4.

Escherichia coli bacteriocin: antimicrobial efficacy and prevalence among isolates from patients with bacteraemia.

Due to appearance of resistance against colicins, combinations of five colicins are effective during antimicrobial therapy.

COBISS.SI-ID: 2484303

5.

Prevalence and associations of tcpC, a gene encoding a Toll/Interleukin-1 receptor domain-containing protein, among Escherichia coli urinary tract infection, skin and soft tissue infection, and commensal isolates

The prevalence of the tcpC gene is statistically significantly associated with Escherichia coli strains isolated from patients with extraintestinal infections.

COBISS.SI-ID: 2164303