J3-2290 — Annual report 2009
1.
Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation.

Using a rodent model with ablated tryptophan-hydroxylase-1, which lacks peripheral serotonin, authors showed that similar to platellets in the blood, also pancreatic beta-cells require the presence of serotonin and covalent modification (serotonylation) of key proteins in the process of exocytosis, is crutial for correct insulin release.

COBISS.SI-ID: 63941377
2.
Prevalence of stochasticity in experimentally observed responses of pancreatic acinar cells to acetylcholine.

In pancreatic acinar cells authors conclude that mathematical models should take stochasticity explicitly into account when describing intra- and intercellular processes.

COBISS.SI-ID: 13698582