Electrically mediated gene transfer is dependent on electrical parameters used for tissue electroporation. The study evaluated efficacy of different electrical parameters in electrogene transfer and indicates that the best transfection efficacy is obtained using several 600 V/cm electric pulses duration of 5 ms.
COBISS.SI-ID: 737659
Electrochemotherapy uses cytostatics bleomycin or cisplatin that have radiosensitizing effect. Electroporation increses intracellular concentration of both drugs resulting in increased radiosensitization of tumors. The study has indicated as the first that electrochemotherapy is effective also in fractionated radiation regime, both on radisensitive and radioresistant tumors.
COBISS.SI-ID: 823163