P4-0092 — Annual report 2009
1.
Risks of antibiotic residues in milk following intramammary and intramuscular treatments in dairy sheep.

The goal of the study was to describe the excretion rate in lactating ewes following infusion of two antibiotic products registered for use in lactating cattle. The results indicate that patterns of antibiotics excretion differ widely between the ovine and bovine mammary gland. The milk withholding time in ewes require a considerable longer period of retention than that recommended for dairy cows.

COBISS.SI-ID: 3045754
2.
Validation of the procedure for the determination of maduramicin in concentrates, premixes, and feeds by liquid chromatography.

The validation of the procedure for the determination of maduramicin in concentrates, premixes, and feedingstuffs. The analytical procedure consists of the extraction of maduramicin from the sample, derivatisation with dansilhydrazin and determination by liquid chromatography with UV detection.

COBISS.SI-ID: 3020154
3.
Ostreolysin induces sustained contraction of porcine coronary arteries and endothelial dysfunction in middle and large-sized vessels.

Ostreolysin (Oly) is a cytolytic and cardiotoxic protein from the oyster mushroom. The purpose of the study was to show histopathological lesions caused by Oly after parenteral application to rats, and to define the mechanisms of Oly-induced vasoconstriction using in vitro model on porcine coronary artery rings. We found that Oly causes endothelial injury with perivascular oedema in the heart and lungs, as well as myocardial haemorrhages in rats. Treatment of porcine coronary artery rings with Oly causes concentration-dependent vasoconstriction and prevents endothelium-mediated relaxation.

COBISS.SI-ID: 3071866
4.
Factors influencing dissipation of avermectins in sheep faeces

Avermectins are lactone derivatives with potent anthelmintic properties. Factors influencing the degradation of avermectins (abamectin, doramectin) in faeces of treated sheep were investigated under different experimental conditions. In the laboratory, DT50 did not exceed 9 days. In the karst pasture, DT50 was 27 days for abamectin and 23 days for doramectin. Degradation of avermectins in faeces was not affected by the presence or absence of microbes. A possible influence of moisture content of sheep faeces on concentrations of avermectins was observed.

COBISS.SI-ID: 3107706
5.
Identification of SARS-like coronaviruses in horseshoe bats (Rhinolophus hipposideros) in Slovenia

In this study samples were collected from 106 live bats of seven different bat species from 27 different locations in Slovenia. Coronaviruses were detected in 14 out of 36 horseshoe bat (Rhinolophus hipposideros) fecal samples with 38.8 % virus prevalence by RT-PCR method. The potential risk of new group of bat coronaviruses as a reservoir for human infections is highly suspected.

COBISS.SI-ID: 26729689