Twenty-four BALB/c mice were orally inoculated with 10(8) CFU Escherichia coli ATCC 25922 and euthanized 2.5, 7, 13 and 25h post-inoculation. The levels of organ nitric oxide (NO) in lungs, liver, kidneys and brain, and plasma endotoxin, TNF-alpha and nitrite/nitrate (NO(x)) were compared to those found in sham-inoculated mice, to evaluate systemic host-response to a low-level oral exposure to Gram-negative bacteria. Organ NO and plasma TNF-alpha levels were higher in E. coli-inoculated animals, but no differences were detected in plasma endotoxin levels and NO(x) for any of the animal groups. Single oral gavage with live E. coli stimulates an early systemic immune response in clinically healthy mice as evidenced by increased plasma TNF-alpha and organ NO levels.
COBISS.SI-ID: 3335546
The aim of the study was to determine the incidence and most frequent anatomical locations of residual oronasal fistulas in children with different types of clefts. The incidence of clinically significant fistulas that required surgical repair was 2.0%. The low incidence of oronasal fistulas is the result of a surgical technique and tensionless suturing, followed by a two-layer closure, two-stage palate repair in BCLP and UCLP patients and preoperative orthopedics in UCLP cases.
COBISS.SI-ID: 28764377
The paper describes free temporal fascia transfer for the replacement of missing mucosa of the floor of the mouth. Surgery was performed for the first time in Slovenia and represents a contribution to orofacial reconstruction of cancer patients.
COBISS.SI-ID: 28187609