Anterior cruciate ligament (ACL) reconstruction is followed by a prolonged rehabilitation. With the use of growth factors we achieved a faster revacularization and engraftment of ligamentum, which was confirmed by MRI imaging. Local application of GFs stimulating SCs and other cells seems to be reasonable.
COBISS.SI-ID: 3697215
Human adipose-derived stem cells (hASCs) isolated from four donors were grown on decellularized bone scaffolds in perfusion bioreactor. With a combination of hASCs, decellularized bone scaffold, perfusion culture, and osteogenic supplements, 5 week cultivation resulted in the formation of compact and viable bone tissue constructs.
COBISS.SI-ID: 25944537
Anatomically shaped bone constructs are necessary for reconstruction of bone defects. We managed to develop bone constructs in a biomimetic bioreactor by using scaffolds in 5 weeks. The constructs' architecture and composition is consistent with the expected one. The procedure has great implications in the craniofacial and orthopedic surgery.
COBISS.SI-ID: 26093785
Bone defects can be treated with live bone grafts grown in vitro on 3-D scaffolds that were populated by appropriate stem cells. Since the initial harvest is very small it is critically important that the cells are capable of populating the scaffold and differentiate into the bone. We discuss the characteristics and limitations of various types of human embryonic and adult stem cells, and their utility for bone tissue engineering.
COBISS.SI-ID: 27069657
The public cord blood bank is a non-profit organization that processes and stores donated unrelated umbilical cord blood (UCB) for haematopoietic stem cell transplantations. In the past year and half 267 units were stored. The article gives the results and quality of UCB collection in the first 1,5 years. It announces the accreditation process at the international registry EuroCord and compliance with NetCord-FACT standards.
COBISS.SI-ID: 27432153