P3-0293 — Annual report 2010
1.
Prevalence of systemic disease and use of medication in patients referred for periodontal treatment

Medical history from 252 patients were seconded to parodontologu we assessed the frequency of systemic disease and medication. We found that 62% of patients indicates the presence of serving one or more systemic diseases and that 25% take zdravila.Pogostnost systemic disease medication is greater in patients with more extensive form of the advanced periodontal disease. findings show the need for detailed medical history of patients in dental practice.

COBISS.SI-ID: 28153305
2.
Antibiotic prescribing practices among Slovene dentists

In 2009, dentists in Slovenia prescribed prescription 28.8 per 1000 population, which is down 5.4 outpatient antibotikov. Costs for these antibotike totaled € 605,578. In order to slow development and reduce the spread of emergence of resistance mirkoorganizmov, we in dentistry to reduce overall consumption and improve the use of specific classes of antibiotics with more specific regard to the amount of dose and duration of treatment.

COBISS.SI-ID: 28153561
3.
Anti-NGF treatment reduces bone resorption in periodontitis.

In rats, periodontitis was induced and antNGF antibodies were injected intraperitonealy. After antiNGF treatment, destruction of periodontal tissues was less extent in comparison to the control group. The results are indicative for the important role of NGF and neurogenic mechanisms in regulation of periodontal inflammation.

COBISS.SI-ID: 26759641
4.
TLR4 expression in sensory neurons innervating inflamed gingiva in the rat

In rats, trigeminal ganglion neurons were retrogradly labelled with neuron markers. Periodontitis was induced in half of the rats. The expression of TLR4 receptor was evaluated in neurons of trigeminal ganglion that innervate healthy and inflamed gingiva. Results have shown that some neurons that innervate gingiva constitutively express TLR4 receptor and that the expression of the receptor is increased during gingival inflammation. According to the results, neurons that innervate gingiva are able to recognise the presence of bacterial products in gingiva.

COBISS.SI-ID: 28152025
5.
Expression levels of endothelin-1, endothelin-2, and endothelin-3 vary during the initial, lag, and late phase of orthodontic tooth movement in rats

The involvment of three endothelin isopeptids during the initial, lag and late phase of orthodontic tooth movement were determined. The results showed that ET-1 and ET-3 are involved in all three phases. ET-1 had a predominant role in the late phase.

COBISS.SI-ID: 27069401