Latest results on urothelial differentiation were presented. It was described how Golgi rearrangements enable assembly of urothelial plaques from 16-nm uroplakin particles, which lead to the formation of functional permeability barrier of superficial urothelial cells. It was further shown, how endocytosis contributes to the maturation of the apical plasma membrane and mechanisms that inhibit endocytosis in terminally differentiated urothelial cells.
B.04 Guest lecture
COBISS.SI-ID: 25974745Anthology in the honour of 90th anniversary of Medical faculty in Ljubljana includes a chapter on the Institute of Cell Biology. The chapter describes history, academic activity and scientific work on the Institute.
C.02 Editorial board of a national monograph
COBISS.SI-ID: 248101888The aim of doctoral thesis was study of formation and vesicular traffic of asymmetric unit membrane during normal urothelial differentiation and during regeneration after damage. New methods of immuno-electron microscopy and electron tomography were introduced. The main result of this work was presentation of integral model of biosynthetic pathways in urothelial cells.
D.09 Tutoring for postgraduate students
COBISS.SI-ID: 245896960The overview gives a detailed survey about the proteins associated with tight junctions, their structure and functions. We summarized our knowledge about tight junction proteins and their involvement in some diseases. The article is meant as a literature for graduate and postgraduate students.
D.10 Educational activities
COBISS.SI-ID: 26743001The work is a survey of our own and current knowledge on autophagy, a catabolic process of the degradation of cellular components. The connections between autophagic malfunctioning and many human diseases are explained. The article is supplementary literature for students of different study programmes.
D.10 Educational activities
COBISS.SI-ID: 26743769