The aim of the study was to characterize the normal bacterial flora and evaluate the presence of periodontopathogenic bacteria around dental implants and to correlate them with the periodontal flora or, in completely edentulous patients, the alveolar gingival flora. In healthy peri-implant sulci, oral streptococci constitute the predominant bacterial flora. In partially edentulous patients four periodontopathogenic bacteria were detected around implants, and none of these bacteria were found around implants in completely edentulous patients.
COBISS.SI-ID: 27269081
5-Benzylidenethiazolidin-4-ones and 5-benzylidenepyrimidine-4,6-diones (compounds 1–9), and rhodanine derivatives 10 and 11 were synthesized and assayed in vitro for their antimicrobial activity against four standard bacterial strains. Compaund (1) inhibited the growth of S. aureus at 0.5 µg/mL and MRSA at 32 µg/mL. Stronger antimicrobial activity against S. aureus was observed for compounds bearing the rhodanine ring than those containing other heterocyclic moieties. Neither of the compounds 1–11 inhibited the growth of Gram-negative bacteria E. coli or P. aeruginosa.
COBISS.SI-ID: 2752113
Determination whether prior exposure to the cryptococcal antigens enhances anticryptococcal activity of cytotoxic cells in mice and the contribution of perforin- and nonperforin-mediated cytotoxicity of NK and T cells in growth inhibition of C. neoformans was studied. Anticryptococcal activity of the NA cells obtained from immunized mice after in vitro incubation with cryptococcal antigens was perforin and nonperforin mediated. In mice a nonperforin-mediated pathway of anticryptococcal cytotoxicity can be induced by immunization.
COBISS.SI-ID: 27334617
Molecular characteristics of animal norovirus and sapovirus strains were presented for the first time in Slovenia. Noroviruses were detected only in pigs located in one specific farm. They were showing less genetic diversity compared to sapoviruses. Sapoviruses were detected on 5 different farms and according to the phylogenetic analysis they were grouped into four distinct genotypes. The study presents important information of norovirus and sapovirus diversity in healthy animals, which are supposed to be a possible reservoir of new emerging viruses.
COBISS.SI-ID: 26729945
In this study, which included 46 patients with acute Crimean-Congo haemorrhagic fever, hospitalized in Kosovo between 2001 and 2007, we showed that viral load seems to be strongly related to the severity and outcome of the disease. We found that virus concentrations of 108 copies RNA/ml of sample or higher indicate a poor prognosis. We demonstrated that higher concentrations of IL-10, INF-? and TNF-? cytokines are associated with a more severe course of the disease. In addition, a positive linear dependence between viral load and these cytokines was observed.
COBISS.SI-ID: 27118553