P2-0249 — Final report
1.
Electroporation device

The clinical electroporation device Cliniporator was developed as a result of our past collaboration with an Italian-based company for clinical biophysics, IGEA. With respect to the economic impact of this partnership, the company recorded substantial growth between the years 2006 and 2012 in both, revenues as well as the number of employees. Its total revenues more than doubled in this time period, the increase in Oncology alone was 15-fold. The number of employees increased by 75%, from 49 in 2006 to 85 in 2012. The success and economic growth is in part based on patent no. US 7625729 B2, Dec. 1. 2009, application no. 10/517,038, PTC filed Jun. 10, 2003, United States Patent and Trademark Office, which is licensed to IGEA SpA exclusively.

F.21 Development of new health/diagnostic methods/procedures

COBISS.SI-ID: 8295764
2.
Organization of the international scientific workshop and postgraduate course "Electroporation-based Technologies and Treatments"

In November 2014, we successfully organized and carried out the 8th international scientific workshop and postgraduate course "Electroporation-based technologies and treatments". The workshop was first organized in 2003 and started as a biennial event. Due to its success and increased interest of students and researchers in the field, it became an annual event. So far we have hosted over 500 atendees from 31 different countries. The lecturers are the most eminent and established international experts in electroporation, such as Eberhard Neumann, Justin Teissié, Lluis M. Mir, Veronique Préat, P. Thomas Vernier, Mounir Tarek, Marie-Pierre Rols, Javier Raso, Emmanuela Signori, James C. Weaver, Dietrich Knorr, Boris Rubinsky, Rafael Davalos, David Dean, Damijan Miklavčič, Tadej Kotnik, Gregor Serša, Maja Čemažar, Gintautas Saulis, Declan Soden, Eugene Vorobiev. Between the years 2009-2014, the event was organized five times and was attended by more than 270 different lecturers and students from 28 countries. The postgraduate course is a part of the credit system of the EU doctoral studies programmes and is also acredited with Slovenian Medical Chamber, so that medical doctors attending the school receive CME (Continuing Medical Education) certificate.

B.01 Organiser of a scientific meeting

COBISS.SI-ID: 276207616
3.
Invited lecture "Electrochemotherapy - electric pulses increasing effectiveness of cancer drugs" and an international award

The programme leader Prof. Dr. Damijan Miklavčič had an invited lecture at the World Congress on Medical Physics and Biomedical Engineering, held from 26th to 31st May 2012 in Beijing, describing electrochemotherapy, and was awarded the Zworykin Award of the International Federation for Medical and Biological Engineering (IFMBE) for his achievements in this field.

E.02 International awards

COBISS.SI-ID: 9219156
4.
Editor of a scientific monograph "Advanced electroporation techniques in biology and medicine", CRC Press

The book Advanced Electroporation Techniques in Biology and Medicine consists of 27 chapters spanning 501 pages, written by the leading experts on electroporation techniques in biology and medicine. The authors present the basic techniques applied in electroporation and the advanced methods for creation of nanopores, highlighting their basic science and clinical applications. Topics include nano-electroporation, classic electroporation, experimental evidence for electroporation of living cells, and electroporation for cancer and wound healing. The programme leader, Prof. Dr. Damijan Miklavčič co-edited this book with Andrei G. Pakhomov (Old Dominion University, USA) and Marko S. Markov (Research International, Buffalo, USA).

C.01 Editorial board of a foreign/international collection of papers/book

COBISS.SI-ID: 7764052
5.
ECTplan

In the scope of the project, we developed ECTplan, a web-based application intended for use by surgeons and interventional radiologists that use electrochemotherapy to treat deep-seated tumors. ECTplan recieved the Rector’s award for best innovation of the University of Ljubljana of the year 2012. The application consists of automatic medical image analysis and segmentation, reconstruction of the patient’s anatomy and optimization of electrode positions and applied voltages. Compared to conventional solutions, where specialized personel is needed for treatment plan preparation, ECTplan represents a cost-effective solution since the clinicians can prepare the treatment plans autonomously.

E.01 National awards

COBISS.SI-ID: 1654139