The program group member introduced state of the art techniques for simulation of biologically active molecules in the solid state. He also prepared and led the workshop for students, focusing on practical work with molecular simulation program tools.
B.04 Guest lecture
COBISS.SI-ID: 5030938The invention relates to a pharmaceutical composition comprising an ethylene derivatives of tricyclic carbapenems in the form of pure diastereoisomers and in the form of pure geometric isomers or a salt, ester or amide derivate thereof and an antibiotic and the use of this composition as a broad band spectrum betalactamase inhibitor.
F.32 International patent
COBISS.SI-ID: 4059418Disclosed are novel ethylidene derivatives of tricyclic carbapenems, in the form of pure diastereoisomers and in the form of pure geometric isomers. Novel ethylidene derivatives of tricyclic carbapenems are used as inhibitors of the action of the enzyme beta lactamase and/or as antibiotics in human and veterinary medicine. Also disclosed are pharmaceutical formulations for the treatment of bacterial infections of human and animal organisms comprising as an active ingredient a therapeutically effective amount of an ethylidene derivative of tricyclic carbapenems in the form of an acid, a pharmaceutically acceptable salt or ester thereof and optionally in a combination with a beta lactam antibiotic, and usual pharmaceutically acceptable carriers and auxiliary substances. Also disclosed is a process for the preparation of novel ethylidene derivatives of tricyclic carbapenems.
F.32 International patent
COBISS.SI-ID: 2931482Janez Mavri is member of the editorial board. In 2011 he was guest editor of a special issue dedicated to 90th anniversary of Academician Dušan Hadži.
C.03 Guest-associated editor
In the scope of the subject Pharmaceutical Chemistry III, part of the undergraduate curriculum at the Faculty of Pharmacy, University of Ljubljana the textbook Medicinal chemistry III: laboratory practice and seminars was published. Researcher contribution chapter: Introduction to molecular modeling).
D.10 Educational activities
COBISS.SI-ID: 252671232