L4-1046 — Final report
1.
Improved affinity selection of ligands from phage-displayed libraries : European patent no. EP7112356.6,

Authors: LUNDER, Mojca, BRATKOVIČ, Tomaž, EKAR, Petra, KREFT, Samo, URLEB, Uroš, ŠTRUKELJ, Borut Description: Together with LEK Sandoz Pharmaceutical Company we successfuly developed a novel method for affinity selection of peptidi ligands from phage-displayed libraries that enable faster development of biopharmaceuticals and might be used in broader life science fields

F.09 Development of a new technological process or technology

COBISS.SI-ID: 2271345
2.
Ultrasound elution of biological ligands

Authors: LUNDER, Mojca, BRATKOVIČ, Tomaž, URLEB, Uroš, KREFT, Samo, ŠTRUKELJ, Borut, EKAR, Petra Description: We apply fro the patent on the development of specifi ultrasound elution method, useful in pharmacy and in broad biological science

F.10 Improvements to an existing technological process or technology

COBISS.SI-ID: 2613361
3.
Genetically modified food grade microorganism for treatment of inflammatory bowel disease : Applicant's reference P003127EP

Authors: LUNDER, Mojca, RAVNIKAR, Matjaž, ŠTRUKELJ, Borut, BERLEC, Aleš, ČEH, Boris Description: A patent application was sent for the protection of novel GMO lactocccus bearing the hipervariability region that strongly binds to TNFalfa in order to develop the biological drug against chronic bowel inflammatory disease

F.21 Development of new health/diagnostic methods/procedures

COBISS.SI-ID: 2770801
4.
Gold award: development of recombinant probiotics against inflammatory bowel disease

Authors: ŠTRUKELJ, Borut, LUNDER, Mojca, RAVNIKAR, Matjaž, BERLEC, Aleš description: This is one of three awards dedicated to our novel technology on the development of anti-inflammatory bowel disease biopharmaceuticals by using phage display technology

F.21 Development of new health/diagnostic methods/procedures

COBISS.SI-ID: 2919793
5.
Peptide phage display as a tool for drug discovery: targeting membrane receptors

Authors: MOLEK, Peter, ŠTRUKELJ, Borut, BRATKOVIČ, Tomaž Description: Article deals with the review of the use of phage display as a tool in developing modern biopharmaceuticals and other peptide molecules with the affinity to membrane receptors

F.02 Acquisition of new scientific knowledge

COBISS.SI-ID: 2951537