L3-0328 — Annual report 2009
1.
Serum cystatin C-based formulas for prediction of glomerular filtration rate in patients with chronic kidney disease

Glomerular filtration rate (GFR) of 592 adult patients with chronic kidney disease (CKD) was estimated using five equations based on serum cystatin C: Larsson, Hoek, Grubb, simple cystatin C formula (GFR=100/cystatin C) and our own cystatin C formula (GFR=90.63 x cystatin C -1.192)). The GFR was measured using CrEDTA clearance. Our results indicate that all serum cystatin C-based equations, excluding the Larsson formula, are reliable markers of GFR in patients with CKD and for daily clinical practice the simplest formula (100/cystatin C) could be appropriate enough for GFR estimation.

COBISS.SI-ID: 3469375