The article aims to explain significant intensity differences between erythrocyte and platelet regions in T1-weighted MR images. The differences were confirmed by immunohistology as well as by relaxation time differences between the two clot regions.
COBISS.SI-ID: 21922087
An efficient method for prognosis of the outcome of a thrombolytic intervention could help choosing the most appropriate treatment method. In this article we have published results showing that apparent diffusion constant (ADC) mapping of a blood clot provides a better and completer information on its retraction and its dissolution properties than more commonly used T2 relaxation time mapping of the clot. The described method of clot dissolution properties assessment based on ADC mapping of the clot may have in future a significant clinical relevance.
COBISS.SI-ID: 23046183
Experiments with optical microscopy published in this article confirmed our assumption that clot degradation products in thrombolysis appear in a form of blood cell clusters (mainly erythrocytes), whose size is highly dependent on the blood flow rate through the channel of the clot. Thus, the faster flow tears on average, larger clusters of cells, while the slower flow tears clusters are much smaller. The observed results also provide a microscopic explanation for the well-known fact in clinical practice that thrombolysis without blood flow or in slow flow is very slow.
COBISS.SI-ID: 23815719
In this paper results of mathematical modeling of plasma and thrombolytic agent permeation into non-occlusive blood clots are presented. The results are supported also with magnetic resonance imaging of plasma permeation into clots. The clots were made of venous blood and were dynamically imaged in an artificial perfusion system.
COBISS.SI-ID: 21921831
Described is a case of a patient for whom it was not possible to set the correct diagnosis only from the ECG recording, but only when it was interpreted in the context with his chest abnormalities.
COBISS.SI-ID: 27268825