J3-0394 — Annual report 2008
1.
Bisoprolol vs. carvedilol in elderly patients with heart failure: rationale and design of the CIBIS-ELD trial.

Aim: To compare the tolerance of bisoprolol and carvedilol in elderly patients with CHF. Methods: CIBIS-ELD is an investigator-initiated, multi-centre, 1:1 randomised, double-blind, phase III trial comparing bisoprolol and carvedilol in patients ‡65 years with systolic or diastolic CHF. Perspective: This is the first large scale head to head betablockers trial in an elderly population with CHF. We expect to gain further insight into the treatment of the particular population of patients with diastolic CHF.

COBISS.SI-ID: 24676569
2.
Challenges of beta blocker therapy in chronic heart failure: the story continues.

Beta blockers are underused and underprescribed in patients with chronic heart failure. This may be due to poor patient knowledge about their condition, pharmacological treatment and self-care management in case of deterioration. Nurse specialist has a decisive role in implementation of evidence based management which can have effects beyond patient care.

COBISS.SI-ID: 24554201