J1-0308 — Annual report 2009
1.
Discovery of DNA gyrase inhibitors.

Our results on discovery of novel inhibitors of DNA gyrase using structure-based design and characterisation by biophysical methods were presented

B.03 Paper at an international scientific conference

COBISS.SI-ID: 2577777
2.
Structure-based discovery of novel bacterial gyrase inhibitors.

In the lecture we have revealed how the use of virtual screening based on cyclothialidine complex with DNA gyrase B enabled the discovery of novel analogs without lactone ring which renders the molecules pharmacokinetically unfavorable.

B.03 Paper at an international scientific conference

COBISS.SI-ID: 4174874