1.

Glutathione level after long-term occupational elemental Hg exposure

Many in vitro and in vivo studies have elucidated the interaction of inorganicmercury (Hg) and glutathione. However, human studies are limited. In this study, we investigated the potential effects of remote long-term intermittent occupational elemental Hg vapour (Hg°) exposure on erythrocyte glutathione levels and some antioxidative enzyme activities in ex-mercury miners in the period after exposure

COBISS.SI-ID: 20977959

2.

Molecular impact of glutathione peroxidases in antioxidant processes

Reactive oxygen species are produced during different pathological processes in increased concentrations. They cause lipid peroxidation and oxidation of DNA and proteins due to their high chemical reactivity. However, antioxidative defense mechanisms, including different antioxidant enzymes, prevent tissue damages and other ROS-related complications. The focus of this review is on effects of different glutathione peroxidases (GPXs) on molecular control of reactive oxygen species toxicology. Furthermore, specific biochemical properties, synthesis and role of each GPX isoenzyme are described.

COBISS.SI-ID: 2352497