We have identified an interaction between stefin B and the histones. Increased expression of stefin B in the nucleus influenced processing of CUX1 transcription factor, and as a consequence of diminished cleavage of CUX1, delayed cell cycle progression was determined. Interaction of stefin B with the truncated form of cathepsin L in the nucleus was confirmed by FRET experiments in the living cells.
B.03 Paper at an international scientific conference
COBISS.SI-ID: 4261402Project leader presented recent discoveries about the role of interellular inhibitors of cysteine cathepsin in activated macrophages in section Recent developments; Society for Leukocyte Biology,
B.04 Guest lecture
COBISS.SI-ID: 23121959Project leader had a lecture for the pharmacy, biology and medicine students of Tuzla University ( BiH) Lecture was about recent developments in teh field of lysosomal proteinases in innate and adaptive immune response.
B.04 Guest lecture
COBISS.SI-ID: 20863015V: 13th International Congress of Immunology, Rio de Janeiro, Brazil, August 21-25,2007. IMMUNO RIO2007In the section Macrophages and Neutrophils project leader had a presentation in which she presented resarch about the role of cysteine cathepsins and intracellular inhibitors (stefin B and SpiA3G) in macrophage activation and upom the induction of experimental endotoxin tolerance.
B.03 Paper at an international scientific conference
COBISS.SI-ID: 21016871Lecture at 7th Meeting of the Slovenian Biochemical Society with International Participation, Maribor, September 26th to 29th, 2007. Lysosomal cathepsins and intracellular inhibitors in endotoxin tolerance. In section Proteins, structure function and regulation project leader had a lecture in which she presented ther ole od lysosomal cathepsins and intracelular inhibitors ( stefin B and SpiA3g) in experimental endotoxin tolerance.
B.03 Paper at an international scientific conference
COBISS.SI-ID: 23217369