L2-7080 — Final report
1.
Preparation of large methacrylate monolithic plates

Pqatent protect procedure for preparation large methacrylate monolithic plates, which can be used in TLC or as a support for microchips.

COBISS.SI-ID: 3388280
2.
Influence of the methacrylate monolith structure on genomic DNA mechanical degradation, enzymes activity and clogging.

Monolith structure was studied via genomic DNA molecules, as an exaple of large asymetric molecule. We focused on clogging and DNA degradation. Based on these experiments we determined most appropriate monolith pore size distribution.

COBISS.SI-ID: 3739418
3.
Purification and concentration of bacteriophage T4 using monolithic chromatographic supports.

In the article we describe purification of fages and confirmation that viability is preserved. Entire procedure is shorter for an order of magnitude in comparison to conventional methods and can be used also for monitoring of phage cultivation.

COBISS.SI-ID: 3408248
4.
Characterization of ion exchange stationary phases via pH transition profiles.

In this article a novel methods for characterization of ion-exchange supports is described. This is a novel technique based on pH transient measurement, which enables non-invasive and rapid determination of ligand density what is a crucial factor for monolith technology.

COBISS.SI-ID: 3442296
5.
Characterisation of grafted weak anion-exchange methacrylate monoliths

Here a novel chromatographic support, based on grafting of active groups, is described. The main advantage of this approach is in high dynamic binding capacity. Grafted supports have been characterized with test samples as well as with ream ones demonstrating their superiority.

COBISS.SI-ID: 12459542