The article describes association between mutation in the nuclearly encoded mitochondrial transcription factor TFAM and fat deposition (marbling) in cattle. The inofrmativity and robustness of this marker triggered significant interest for application of this amrker in marker assisted selection.
COBISS.SI-ID: 1739912
The taxonomic status of many fish species is unknown, this is particularly true for many salmonid fishes inhabiting the Balkan Peninsula. One of the endangered trout species in this region is also the softmouth trout (Salmo obtusirostris). Studies based on several genetic markers have shown that the softmouth trout is represented by five distinct genetic lineages. This finding is of crucial importance for conservation and development of appropriate strategies for softmouth trout management.
COBISS.SI-ID: 1851784
Autoimmune regulator (AIRE) was identified as first non-viral eukaryotic activator of type IIA. It recruits positive transcriptional elongation factor b (P-TEFb) to target promoters, which enables the ectopic expression of tissue specific genes in the thymus and leads to establishment of central tolerance.
COBISS.SI-ID: 2213000
The processing of eukaryotic pre-mRNA is coupled with transcription. Demonstrations of connectionsbetween nascent transcripts, splicing factors, and the transcriptional machinery provide reliable evidence that splicing occurs co-transcriptionally. The complexity of co-transcriptional splicing is reflected in the coordinated interplay between various cis-elements and trans-acting factors. In this article, we demonstrated that a cis-element in the intron 1 of the equine b-casein gene (intronic splicing enhancer 1, ISE1) increases the inclusion of all weak exons in its pre-mRNA.
COBISS.SI-ID: 1838472
Mycoplasma species are important pathogen in birds, especially in chickens and turkeys. Factors of pathogenicity in mycoplasmas are not known. In our study we investigated genes coding neuraminidases in M. gallisepticum (MG) and M. synoviae (MS). We introduced a fast and simple test for neuraminidase activity and demonstrated it in MG, MS, some other avian mycoplasma species. We were first group showing neuraminidase activity in mycoplasma species, pathogenic for dogs and cats and in M. neurolyticum, which is causing disease of the central nerve system, probably acting as neurotoxin.
COBISS.SI-ID: 2278536