1.

Development of enzyme inhibitors for treatment of neurodegenerative diseases

The results of the research work on the project were presented on a plenary lecture at a congress with international participation.

B.03 Paper at an international scientific conference

COBISS.SI-ID: 4810097

2.

Granted EU and USA patent: Disubstituted piperidine derivatives as butyrylcholinesterase inhibitors for use in the treatment of Alzheimer

The present invention relates to the field of medicinal chemistry and novel 1,3-in 1,4-disubstituted derivatives of piperidine as pharmaceuticall active compounds. These compounds can be in the form of a mixture of enantiomers or in the form of pure enantiomers, in the form of pharmaceutically acceptable salts, as hydrates or solvates thereof. Novel 1,3- and 1,4-disubstituted derivatives of piperidine are inhibitors of the enzyme butyrylcholinesterase. The compounds of the present invention are useful for the treatment of various diseases which may be therapeutically modified by altering the activity of butyrylcholinesterase such as Alzheimer's disease and other dementias

F.32 International patent

COBISS.SI-ID: 4224113

3.

Member of Editorial Board of Acta Chimica Slovenica

The project leader Stanislav Gobec is a member of Editorial Board of international journal Acta Chimica Slovenica. The journal publishes papers fom all fields of chemistry, is cited in all major databases and has Impact Factor.

C.06 Editorial board membership

COBISS.SI-ID: 14086149