J4-9322 — Final report
1.
Effect of humanizing mutations on the stability of the llama single-domain variable region

The article describes possible approaches to mutate nanobodies in order to reduce their immunogenicity but preserve their binding affinity

COBISS.SI-ID: 48829955
2.
Electrochemical immunosensor functionalized with nanobodies for the detection of the toxic microalgae Alexandrium minutum using glassy carbon electrode modified with gold nanoparticles

Development of a new nanobody-based biosensor that possesses high sensitivity and specificity and that can be exploited to quantify analytes present in biological samples

COBISS.SI-ID: 33144103
3.
A compact nanobody-DNAzyme conjugate enables antigen detection and signal amplification

Innovative solution to prepare protein-DNA chimeras with peroxidase activity that can be used for any application exploiting electrochemical conversions to identify and quantify antigens

COBISS.SI-ID: 5479419
4.
Comparative analysis of fusion tags used to functionalize recombinant antibodies

Nanobodies require tags for being effectively transformed into suitable reagents. We undertook a systematic analysis of advantages and drawbacks of conventional and recently proposed tags

COBISS.SI-ID: 5455867
5.
Purification-independent immunoreagents obtained by displaying nanobodies on bacteria surface

Recombinant antibody purification is time-consuming and we explored an alternative procedure for skipping this step and providing a rapid and inexpensive diagnostic method

COBISS.SI-ID: 5374971