V3-1717 — Annual report 2018
1.
The extent of B-cell activation and dysfunction preceding lymphoma development in HIV-positive people

Some markers of B-cell activation and dysfunction (free light chains, levels of IgG, IgM, IgA, IgD) were higher ) 2 years before lymphoma diagnosis, suggesting that B-cell dysfunction occurs many years prior to lymphoma development. However, the predictive value of each marker was low and they are unlikely candidates for risk assessment for targeted intervention

COBISS.SI-ID: 5014188
2.
HIV health care providers are ready to introduce pre-exposure prophylaxis in Central and Eastern Europe and neighbouring countries

PrEP is already used informally in some countries in the region. Physicians are keen to use PrEP if and when it is accessible. Obstacles towards implementing PrEP in those countries were mostly related to lack of national guidelines, drug registration and governmental strategy

COBISS.SI-ID: 5184684
3.
Long-term effectiveness of recommended boosted protease inhibitor-based antiretroviral therapy in Europe

Although confounding by indication and calendar year cannot be completely ruled out, in ARTexperienced subjects the long-term effectiveness of DRV/r-containing regimens appears to be greater than that of ATZ/r and LPV/r

COBISS.SI-ID: 5013676