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Projects / Programmes
The comparative study of porcine and human interferons
Research activity
| Code | Science | Field | Subfield |
|---|---|---|---|
| 1.05.00 | Natural sciences and mathematics | Biochemistry and molecular biology |
| Code | Science | Field |
|---|---|---|
| P004 | Natural sciences and mathematics | Biochemistry, Metabolism |
| P310 | Natural sciences and mathematics | Proteins, enzymology |
Keywords
Interferons, human, porcine, interferon-like proteins, biological effects in vitro, pig as an animal model
Evaluation
(metodology)
Citations
Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
Organisations (1) , Researchers (6)
0381 University of Ljubljana, Faculty of Medicine
| no. | Code | Name and surname | Research area | Role | Period | No. of publicationsNo. of publications |
|---|---|---|---|---|---|---|
| 1. | 03174 | Microbiology and immunology | Researcher | 1999 - 2001 | 159 | |
| 2. | 05320 | Biochemistry and molecular biology | Head | 1996 - 2001 | 271 | |
| 3. | 10337 | Microbiology and immunology | Researcher | 1998 - 2001 | 1,577 | |
| 4. | 07264 | Microbiology and immunology | Researcher | 1996 - 2001 | 226 | |
| 5. | 03172 | Microbiology and immunology | Researcher | 1996 - 2001 | 237 | |
| 6. | 08755 | Microbiology and immunology | Researcher | 2000 - 2001 | 238 |
Abstract
The aim of the project:
(1) Preparing, purification and molecular characterisation of the porcine and human interferons, as well as interferon-like proteins obtained through the electroinduction. The main analysis shows the difference in the glikosilation level.
(2) The comparative analysis of different biological effects of porcine and human interferons as well as interferon-like proteins in vitro in tissue cultures.
(3) Introduction of the pig as animal model for the in vivo tests of human and porcine interferons and interferon-like proteins.