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Projects / Programmes
Serumske vrednosti cisteinskih proteinaz katepsinov B, H in L in njihovih inhibitorjev stefinov in cistatinov kot pokazateljev diagnoze (Slovene)
Research activity
| Code | Science | Field | Subfield |
|---|---|---|---|
| 1.05.00 | Natural sciences and mathematics | Biochemistry and molecular biology |
| Code | Science | Field |
|---|---|---|
| P310 | Natural sciences and mathematics | Proteins, enzymology |
| B200 | Biomedical sciences | Cytology, oncology, cancerology |
Keywords
cathepsins, stefins, cystatin C, cancer, diagnosis, prognosis
Evaluation
(metodology)
Citations
Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
Organisations (3) , Researchers (9)
0106 Jožef Stefan Institute
| no. | Code | Name and surname | Research area | Role | Period | No. of publicationsNo. of publications |
|---|---|---|---|---|---|---|
| 1. | 14315 | Biochemistry and molecular biology | Researcher | 1998 - 2001 | 67 | |
| 2. | 17096 | Biochemistry and molecular biology | Researcher | 1998 - 2001 | 33 | |
| 3. | 18286 | Biochemistry and molecular biology | Researcher | 1998 - 2001 | 138 |
0259 Krka, tovarna zdravil, d.d., Novo mesto (Slovene)
| no. | Code | Name and surname | Research area | Role | Period | No. of publicationsNo. of publications |
|---|---|---|---|---|---|---|
| 1. | 10291 | Pharmacy | Researcher | 1999 - 2001 | 120 | |
| 2. | 04648 | Biotechnical sciences | Head | 1998 - 2001 | 1,221 | |
| 3. | 06394 | Pharmacy | Researcher | 1998 - 2001 | 91 |
0302 Institute of Oncology Ljubljana
| no. | Code | Name and surname | Research area | Role | Period | No. of publicationsNo. of publications |
|---|---|---|---|---|---|---|
| 1. | 03171 | Medical sciences | Researcher | 1998 - 2001 | 286 | |
| 2. | 11949 | Oncology | Researcher | 2000 - 2001 | 710 | |
| 3. | 07195 | Oncology | Researcher | 1998 - 2001 | 120 |
Abstract
The objective of this project is to determine levels of cysteine proteinases cathepsins B, H and L and their inhibitors stefins A and B and cystatin C in sera of patients with malignant melanoma and colorectal cancer using quantitative immunoenzyme assays and to define their potential for prediction of diagnosis, prognosis and response to different chemotherapy in these cancer patients.