Projects / Programmes source: ARIS

Functional interactions between the xenobiotic and lipid signalling pathway

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Research activity

Code Science Field Subfield
1.05.00  Natural sciences and mathematics  Biochemistry and molecular biology   

Code Science Field
P004  Natural sciences and mathematics  Biochemistry, Metabolism 
P310  Natural sciences and mathematics  Proteins, enzymology 
P320  Natural sciences and mathematics  Nucleic acids, protein synthesis 
P340  Natural sciences and mathematics  Lipids, steroids, membranes 
Keywords
Protein interactions, nuclear receptors drug metabolism, lipid homeostasis, functional genomics
Evaluation (metodology)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
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Organisations (1) , Researchers (2)
0381  University of Ljubljana, Faculty of Medicine
no. Code Name and surname Research area Role Period No. of publications
1.  21493  PhD Maja Matis  Neurobiology  Researcher  2005 - 2007  32 
2.  06013  PhD Damjana Rozman  Biochemistry and molecular biology  Head  2005 - 2007  940 
Abstract
Molecular mechanisms underlaying hepatic drug induction through xenosensors and the cross talk with endogenous lipid metabolism are still unclear. This project will study the receptor-protein complexes of transcription factors interacting with xenosensors and their post-transcriptional modifications. Proposed postdoctoral project is embeded into the FP6 STREP EU project Steroltalk. It will contribute to the holistic picture on the signalling complexes that compose the network regulating drug metabolism and sterol homeostasis at the level of proteome. 
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