Projects / Programmes
Lipid peroxidation and functional damage in target tissues and organs in citizens of Idrija and mercury miners exposed to the elemental mercury
Code |
Science |
Field |
Subfield |
3.07.00 |
Medical sciences |
Metabolic and hormonal disorders |
|
Code |
Science |
Field |
B190 |
Biomedical sciences |
Clinical chemistry |
B370 |
Biomedical sciences |
Endocrinology of invertebrates |
B480 |
Biomedical sciences |
Endocrinology, secreting systems, diabetology |
elemental mercury, antioxydants, DNA damages, melatonin, 8-OH-dG
Organisations (4)
, Researchers (17)
0106 Jožef Stefan Institute
0302 Institute of Oncology Ljubljana
no. |
Code |
Name and surname |
Research area |
Role |
Period |
No. of publicationsNo. of publications |
1. |
03279 |
PhD Vera Pompe-Kirn |
Oncology |
Researcher |
2002 - 2004 |
365 |
0312 University Medical Centre Ljubljana
no. |
Code |
Name and surname |
Research area |
Role |
Period |
No. of publicationsNo. of publications |
1. |
18541 |
Matjaž Centa |
|
Researcher |
2002 - 2004 |
0 |
2. |
17160 |
PhD Aleš Jerin |
Cardiovascular system |
Researcher |
2002 - 2004 |
216 |
3. |
21839 |
Mladen Krsnik |
Human reproduction |
Researcher |
2002 - 2004 |
180 |
4. |
10691 |
PhD Joško Osredkar |
Human reproduction |
Head |
2002 - 2004 |
1,337 |
5. |
03893 |
PhD Marija Prezelj |
Human reproduction |
Researcher |
2002 - 2004 |
221 |
6. |
15443 |
MSc Alenka Sešek Briški |
Metabolic and hormonal disorders |
Researcher |
2002 - 2004 |
104 |
0581 University of Ljubljana, Faculty of Arts
no. |
Code |
Name and surname |
Research area |
Role |
Period |
No. of publicationsNo. of publications |
1. |
13425 |
PhD Darja Kobal Grum |
Psychology |
Researcher |
2002 - 2004 |
665 |
Abstract
The overall objective of the proposed study is to analyze and quantify the impact of elemental mercury (HgO) exposure on human health in occupational and ambient exposure in Idrija. The principal objective is to test hypothesis whether the accomulated level of Hg0 in previous and present occupational and ambient exposure (a) promotes lipid peroxidation, which could increase the risk of ishaemic heart disease, (b) influence on central nervous system and kidney and (c) the functional capacity of pineal, pituitary, thyroid and testes glands as a result of higher accumulation of Hg0 in these glands. The study will significantly improve the health surveillance of exposed population to Hg0 through impruved evaluation of specificity of selected bomarkers of early biological effects and initial impairment of functional capacity of target organs and tissues.