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Projects / Programmes source: ARIS

Lipid peroxidation and functional damage in target tissues and organs in citizens of Idrija and mercury miners exposed to the elemental mercury

Research activity

Code Science Field Subfield
3.07.00  Medical sciences  Metabolic and hormonal disorders   

Code Science Field
B190  Biomedical sciences  Clinical chemistry 
B370  Biomedical sciences  Endocrinology of invertebrates 
B480  Biomedical sciences  Endocrinology, secreting systems, diabetology 
Keywords
elemental mercury, antioxydants, DNA damages, melatonin, 8-OH-dG
Evaluation (metodology)
source: COBISS
Organisations (4) , Researchers (17)
0106  Jožef Stefan Institute
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  19724  Vesna Fajon    Researcher  2002 - 2004  300 
2.  10582  PhD Ingrid Falnoga  Neurobiology  Researcher  2002 - 2004  364 
3.  05027  PhD Milena Horvat  Chemistry  Researcher  2002 - 2004  2,027 
4.  14082  PhD Radojko Jaćimović  Physics  Researcher  2002 - 2004  777 
5.  15814  PhD Jože Kotnik  Geology  Researcher  2002 - 2004  406 
6.  04351  PhD Bogdan Kralj  Chemistry  Researcher  2002 - 2004  136 
7.  01873  PhD Vekoslava Stibilj  Chemistry  Researcher  2002 - 2004  690 
8.  08597  Zdenka Trkov    Researcher  2002 - 2004  76 
9.  03950  PhD Dušan Žigon  Chemistry  Researcher  2002 - 2004  182 
0302  Institute of Oncology Ljubljana
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  03279  PhD Vera Pompe-Kirn  Oncology  Researcher  2002 - 2004  365 
0312  University Medical Centre Ljubljana
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  18541  Matjaž Centa    Researcher  2002 - 2004 
2.  17160  PhD Aleš Jerin  Cardiovascular system  Researcher  2002 - 2004  216 
3.  21839  Mladen Krsnik  Human reproduction  Researcher  2002 - 2004  180 
4.  10691  PhD Joško Osredkar  Human reproduction  Head  2002 - 2004  1,337 
5.  03893  PhD Marija Prezelj  Human reproduction  Researcher  2002 - 2004  221 
6.  15443  MSc Alenka Sešek Briški  Metabolic and hormonal disorders  Researcher  2002 - 2004  104 
0581  University of Ljubljana, Faculty of Arts
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  13425  PhD Darja Kobal Grum  Psychology  Researcher  2002 - 2004  665 
Abstract
The overall objective of the proposed study is to analyze and quantify the impact of elemental mercury (HgO) exposure on human health in occupational and ambient exposure in Idrija. The principal objective is to test hypothesis whether the accomulated level of Hg0 in previous and present occupational and ambient exposure (a) promotes lipid peroxidation, which could increase the risk of ishaemic heart disease, (b) influence on central nervous system and kidney and (c) the functional capacity of pineal, pituitary, thyroid and testes glands as a result of higher accumulation of Hg0 in these glands. The study will significantly improve the health surveillance of exposed population to Hg0 through impruved evaluation of specificity of selected bomarkers of early biological effects and initial impairment of functional capacity of target organs and tissues.
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