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Projects / Programmes
Biofarmacevtske lastnosti, sinteza in aktivnost spojin kinolonov s kovinskimi atomi (Slovene)
Research activity
| Code | Science | Field | Subfield |
|---|---|---|---|
| 1.09.00 | Natural sciences and mathematics | Pharmacy |
| Code | Science | Field |
|---|---|---|
| T410 | Technological sciences | Pharmaceuticals and related technologies |
Keywords
fluoroquinolones, pharmacokinetic properties, metallic complexes, antimicrobial activity, erythrocyte uptake of drugs
Evaluation
(metodology)
Citations
Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
Organisations (2) , Researchers (15)
0787 University of Ljubljana, Faculty of Pharmacy
| no. | Code | Name and surname | Research area | Role | Period | No. of publicationsNo. of publications |
|---|---|---|---|---|---|---|
| 1. | 11124 | Pharmacy | Researcher | 1999 - 2001 | 382 | |
| 2. | 17432 | Researcher | 1999 - 2001 | 0 | ||
| 3. | 11789 | Pharmacy | Researcher | 2000 - 2001 | 618 | |
| 4. | 16107 | Pharmacy | Researcher | 1999 - 2001 | 461 | |
| 5. | 17433 | Researcher | 1999 - 2001 | 0 | ||
| 6. | 17434 | Researcher | 1999 - 2001 | 0 | ||
| 7. | 00184 | Pharmacy | Researcher | 1999 - 2001 | 488 | |
| 8. | 11122 | Pharmacy | Head | 1999 - 2001 | 350 | |
| 9. | 09032 | Pharmacy | Researcher | 2000 - 2001 | 940 | |
| 10. | 17430 | Researcher | 1999 - 2001 | 0 | ||
| 11. | 06086 | Pharmacy | Researcher | 1999 - 2001 | 1,166 | |
| 12. | 09066 | Pharmacy | Researcher | 1999 - 2001 | 303 | |
| 13. | 09031 | Pharmacy | Researcher | 1999 - 2001 | 676 |
0103 University of Ljubljana, Faculty of Chemistry and Chemical Technology
| no. | Code | Name and surname | Research area | Role | Period | No. of publicationsNo. of publications |
|---|---|---|---|---|---|---|
| 1. | 03439 | Chemistry | Researcher | 1999 - 2001 | 544 | |
| 2. | 16025 | Chemistry | Researcher | 1999 - 2001 | 127 |
Abstract
The aim of the project is the synthesis together with structural, biopharmaceutic and microbiological assessment of the properties od metal-quinolone compounds. Transport properties and therapeutic potential of compounds of the fluoroquinolone type that are bound in a complex with metal atoms potentially exerting synergistic effects will be studied. Special interest will be put on the influence of the presence and the type of metallic atom in in vitro and ex-vivo systems on the rate and extent of the transport of the quinolones accross biologic membranes.