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Effects of vinblastine and surfactants on threshold voltage for electroporation (post-doc)

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Research activity

Code Science Field Subfield
2.06.07  Engineering sciences and technologies  Systems and cybernetics  Biomedical technics 

Code Science Field
B001  Biomedical sciences  General biomedical sciences 
B002  Biomedical sciences  Biophysics 
Keywords
vinblastine, vinca alcaloids, surfactants, electroporation, electroporation threshold
Evaluation (metodology)
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Organisations (1) , Researchers (1)
1538  University of Ljubljana, Faculty of Electrical Engineering
no. Code Name and surname Research area Role Period No. of publications
1.  18619  PhD Maša Kandušer  Pharmacy  Head  1999 - 2001  175 
Abstract
Electroporation is plasma membrane phenomena where applied electrical field destabilizes the cell membrane making it transiently permeable. Electric field must reach critical value that causes structural changes on membrane that lead to electroporation. Critical value of electric field needed for electroporation is called threshold voltage. The aim of proposed project is to determine the influence of different surfactants and vinblastine on reversible and irreversible threshold voltage for electroporation.
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