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Projects / Programmes
Vpliv nepravilnosti jedra in apoptoze moških semenčic na oploditev in kvaliteto zarodkov (Slovene)
Research activity
| Code | Science | Field | Subfield |
|---|---|---|---|
| 3.05.00 | Medical sciences | Human reproduction |
| Code | Science | Field |
|---|---|---|
| B726 | Biomedical sciences | Clinical biology |
| B570 | Biomedical sciences | Obstetrics, gynaecology, andrology, reproduction, sexuality |
Keywords
human spermatozoa / chromatin / DNK / apoptosis / fertilization / embryos
Evaluation
(metodology)
Citations
Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
Organisations (1) , Researchers (11)
0312 University Medical Centre Ljubljana
| no. | Code | Name and surname | Research area | Role | Period | No. of publicationsNo. of publications |
|---|---|---|---|---|---|---|
| 1. | 15071 | Human reproduction | Researcher | 2000 - 2001 | 93 | |
| 2. | 16361 | Animal production | Researcher | 1999 - 2001 | 983 | |
| 3. | 08772 | Human reproduction | Researcher | 1999 - 2001 | 614 | |
| 4. | 17644 | Researcher | 1999 - 2001 | 65 | ||
| 5. | 10458 | Human reproduction | Researcher | 1999 - 2001 | 915 | |
| 6. | 14534 | Human reproduction | Researcher | 1999 - 2001 | 23 | |
| 7. | 07007 | Human reproduction | Researcher | 1999 - 2001 | 655 | |
| 8. | 11366 | Human reproduction | Researcher | 1999 - 2001 | 75 | |
| 9. | 12245 | Human reproduction | Researcher | 1999 - 2001 | 72 | |
| 10. | 06087 | Human reproduction | Head | 1999 - 2001 | 531 | |
| 11. | 19449 | Human reproduction | Researcher | 1999 - 2001 | 308 |
Abstract
In patients, included in program of assissted reproduction, sperm abnormalities - abnormal sperm chromatin condensation, sperm deoxyribonucleic acid (DNA) fragmentation, chromosomal abnormalities, apoptosis (programmed cell death) will be investigated in association with classic parameters of sperm quality (sperm concentration, number, motility, morphology) and ultrastructural changes of spermatozoa (nucleus, cell organels, membranes). Then the impact of investigated sperm abnormalities on fertilization, embryo development, and embryo quality in program of in vitro fertilization (IVF) will be evaluated. The impact of environmental effects and life-style on observed parameters of sperm quality will be evaluated by the questionnaire.