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Projects / Programmes
Nivo cistatina C in katepsinov B, H in L v bioloških tekočinah zdravih oseb in astmatikov (Slovene)
Research activity
| Code | Science | Field | Subfield |
|---|---|---|---|
| 3.01.00 | Medical sciences | Microbiology and immunology |
| Code | Science | Field |
|---|---|---|
| B540 | Biomedical sciences | Respiratory system |
| B190 | Biomedical sciences | Clinical chemistry |
Keywords
circadian variations, asthma, cystatin C, cathepsin B, cathepsin H, cathepsin L
Evaluation
(metodology)
Citations
Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
Organisations (2) , Researchers (5)
1613 University Clinic of Respiratory and Allergic Diseases
| no. | Code | Name and surname | Research area | Role | Period | No. of publicationsNo. of publications |
|---|---|---|---|---|---|---|
| 1. | 06630 | Biochemistry and molecular biology | Head | 2000 - 2001 | 362 | |
| 2. | 09808 | Cardiovascular system | Researcher | 1998 - 2001 | 357 |
0259 Krka, tovarna zdravil, d.d., Novo mesto (Slovene)
| no. | Code | Name and surname | Research area | Role | Period | No. of publicationsNo. of publications |
|---|---|---|---|---|---|---|
| 1. | 10291 | Pharmacy | Researcher | 1999 - 2001 | 120 | |
| 2. | 04648 | Biotechnical sciences | Researcher | 2000 - 2001 | 1,221 | |
| 3. | 06394 | Pharmacy | Researcher | 2000 - 2001 | 91 |
Abstract
The objective of this project is to determine levels of cystatin C and cathepsins B, H and L in biological fluids of healthy and asthmatic subjects. The purpose is also to establish their normal serum base-line circadian characteristics and their deviations before and after cortisteroid and cyclosporine A treatment. The results may provide better understanding of the role of cysteine proteinases and their inhibitors in pathophysiological mechanisms and may be of clinical interest as additional biochemical parameters for monitoring the disease and its therapy.