UHPLC system coupled to mass detector (UHPLC-MS)

The liquid chromatography-mass spectrometry (LC-MS) system is specifically designed for the qualitative and quantitative assessments of small molecules present in various types of samples. Analytes are first separated using an ultra-high performance liquid chromatograph (UHPLC). The provided system supports very high pressures, which facilitates the use of highly efficient columns that significantly improve the quality of analyte separation. After separation, the analytes are directed to the mass spectrometer (MS). The mass spectrometer used in this system is of the triple quadrupole type, renowned for its exceptional sensitivity, selectivity, and robustness. It allows monitoring the progress of chemical syntheses, for confirming the identity of compounds and determining the concentration of specific compounds in challenging matrices such as cells, plasma, and blood.

Responsible for equipment:
The equipment can be found at the Faculty of Pharmacy, located at Aškerčeva 7, 1000 Ljubljana. Access is possible upon agreement with the equipment's caretaker. Given the specialized nature of the equipment, it is required that the caretaker be present throughout the duration of its use.