Microfluidic device for the preparation of lipid nanoparticles

The microfluidic device allows the preparation of large quantities of lipid nanoparticles, with well-defined formulation and physical properties. These include the chemical formulation (content of individual lipid components), the size and shape of the lipid nanoparticles and the amount of encapsulated material within the lipid nanoparticles. It allows the reliable preparation of potential therapeutic agents already at the pre-clinical level. The device allows the packaging of different nucleic acids and proteins (and other biological agents) and combinations of both into lipid nanoparticles with predefined properties.

Responsible for equipment: PhD Martina Mohorčič
The equipment is accessible to all internal and external users. All users must have adequate knowledge and experience to operate the equipment independently. In the case of non-experienced users, the operators or the Infrastructure facility shall carry out their experiments. In all cases, the project, the complexity of the analyses and the complexity of the samples must be evaluated before the experiments are started.